(S)-3-(5-(4-((1-(4-((1R,2S)-6-Hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 99% 98% ee, 99% 98% ee

cas: 2229711-68-4 — zobacz wszystkie produkty o tym numerze CAS, także pod innymi nazwami

(S)-3-(5-(4-((1-(4-((1R,2S)-6-Hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 99% 98% ee, 99% 98% ee (CAS 2229711-68-4) to odczynnik chemiczny dostępny w ofercie Chemat. Dostępne opakowania: 250mg, 1g, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg. Oferty producentów: Chemat.

• 2D
• 3D

(3S)-3-[6-[4-[[1-[4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione (CAS 2229711-68-4) to związek chemiczny o wzorze sumarycznym C45H49N5O4 i masie molowej 723.9 g/mol. Nazwa systematyczna IUPAC: (3S)-3-[6-[4-[[1-[4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione. InChIKey: TZZDVPMABRWKIZ-XMOGEVODSA-N.

Dane identyfikacyjne

Wzór sumaryczny	C45H49N5O4
Masa molowa	723.9 g/mol
Nazwa IUPAC	(3S)-3-[6-[4-[[1-[4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
InChIKey	TZZDVPMABRWKIZ-XMOGEVODSA-N
SMILES	C1CC2=C(C=CC(=C2)O)[C@H]([C@H]1C3=CC=CC=C3)C4=CC=C(C=C4)N5CCC(CC5)CN6CCN(CC6)C7=CC8=C(C=C7)C(=O)N(C8)[C@H]9CCC(=O)NC9=O

Dane obliczone przez PubChem (NCBI)

Synonimy: Vepdegestrant, Arv 471, PROTAC Protein Degrader ARV-471, ER alpha PROTAC Protein Degrader ARV-471, Estrogen Receptor alpha PROTAC Protein Degrader ARV-471, ER alpha Proteolysis-targeting Chimera Protein Degrader ARV-471, Veppanu (TN), vepdegestrant [INN], starbld0006985, Vepdegestrant [WHO-DD]

Powiązane formy tego związku

(3S)-3-[6-[4-[[1-[4-(6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione C₄₅H₄₉N₅O₄

3-[6-[4-[[1-[4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione C₄₅H₄₉N₅O₄

Izomery (ten sam wzór sumaryczny)

(3S)-3-[6-[4-[[1-[4-[(E)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione C₄₅H₄₉N₅O₄