δ–Secretase inhibitor 11 cas: (842964-18-5)

nazwa: δ–Secretase inhibitor 11

nr katalogowy: GC66048-100

cas: 842964-18-5

producent: GLPBio

opakowanie: 100mg

cena: 1701,64 [Pln] (bez rabatu)

wyszukaj podobne produkty: 842964-18-5


szczegóły:

Formula: C10H12N4O2. Molecular weight: 220,23. Solubility: DMSO : 125 mg/mL (567.59 mM, Need ultrasonic). Storage: Store at -20°C. Synonym: δ-Secretase inhibitor 11 (compound 11) is an orally active, potent, BBB-penetrated, non-toxic, selective and specific δ-secretase inhibitor, with an IC50 of 0.7 μM. δ-Secretase inhibitor 11 interacts with both the active site and allosteric site of δ-secretase. δ-Secretase inhibitor 11 attenuates tau and APP (amyloid precursor protein) cleavage. δ-Secretase inhibitor 11 ameliorates synaptic dysfunction and cognitive impairments in tau P301S and 5XFAD transgenic mouse models. δ-Secretase inhibitor 11 can be used for Alzheimer's disease research..

właściwości

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czas dostawy: Do potwierdzenia przez Chemat