nazwa: δ–Secretase inhibitor 11
nr katalogowy: GC66048-25
cas: 842964-18-5
producent: GLPBio
opakowanie: 25mg
cena: 919,99 [Pln] (bez rabatu)
wyszukaj podobne produkty: 842964-18-5
Formula: C10H12N4O2. Molecular weight: 220,23. Solubility: DMSO : 125 mg/mL (567.59 mM, Need ultrasonic). Storage: Store at -20°C. Synonym: δ-Secretase inhibitor 11 (compound 11) is an orally active, potent, BBB-penetrated, non-toxic, selective and specific δ-secretase inhibitor, with an IC50 of 0.7 μM. δ-Secretase inhibitor 11 interacts with both the active site and allosteric site of δ-secretase. δ-Secretase inhibitor 11 attenuates tau and APP (amyloid precursor protein) cleavage. δ-Secretase inhibitor 11 ameliorates synaptic dysfunction and cognitive impairments in tau P301S and 5XFAD transgenic mouse models. δ-Secretase inhibitor 11 can be used for Alzheimer's disease research..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat