nazwa: (+)–ZK 216348
nr katalogowy: GB40042-2
cas: 669073-68-1
producent: GLPBio
opakowanie: 2mg
cena: 2347,55 [Pln] (bez rabatu)
wyszukaj podobne produkty: 669073-68-1
Formula: C24H23F3N2O5. Molecular weight: 476,45. Solubility: DMSO : 200 mg/mL (419.77 mM, Need ultrasonic). Synonym: Selective nonsteroidal glucocorticoid receptor (GR) agonist for the treatment of experimental colitis with IC50 values of 20, 20, and 80 nM for GR, Progesterone (PR) and Mineralocorticoid (MR) receptors respectively. (+)-ZK 216348 shows antiinflammatory activity comparable to prednisolone for both systemic and topical application, with a significant dissociation between transrepression and transactivation of antiinflammatory effects both in vitro and in vivo.(+)-ZK 216348 showed no negative effects on intestinal epithelial migration or proliferation. (-)-ZK 216348 is completely inactive (IC50 >1000 nM for GR, PR, and MR..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat