(Des–Glu²²)–Amyloid β–Protein (1–40) cas: (1678416-36-8)

nazwa: (Des–Glu²²)–Amyloid β–Protein (1–40)

nr katalogowy: GA20095-1

cas: 1678416-36-8

producent: GLPBio

opakowanie: 1mg

cena: 3157,27 [Pln] (bez rabatu)

wyszukaj podobne produkty: 1678416-36-8


szczegóły:

Formula: C189H288N52O55S. Molecular weight: 4200,75. Solubility: Soluble in DMSO. Storage: Store at -20°C. Synonym: The Osaka mutation was the first deletion-type mutation to be identified in APP and Aβ.The Aβ E22delta mutant is more resistant to degradation by two major Aβ-degrading enzymes, neprilysin and insulin-degrading enzyme. Synthetic mutant Aβ showed unusual aggregation properties with enhanced oligomerization but no fibrillization. It also inhibited hippocampal long-term potentiation more efficiently than wild-type Aβ. A transgenic mouse model containing APP with the E693delta mutation has been developed. APP(OSK)-Tg mice exhibit intraneuronal Aβ E22delta oligomers and memory impairment as early as eight months of age..

właściwości

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czas dostawy: Do potwierdzenia przez Chemat