nazwa: (S,R)–WT IDH1 Inhibitor 2
nr katalogowy: GC65883-10
cas: 1816272-18-0
producent: GLPBio
opakowanie: 10mg
cena: 5680,06 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1816272-18-0
Formula: C28H28FN5O3. Molecular weight: 501,55. Storage: Store at -20°C. Synonym: (S,R)-WT IDH1 Inhibitor 2 (GSK321) is a potent, selective mutant IDH1 inhibitor with IC50 values of 2.9, 3.8, 4.6 and 46 nM for R132G, R132C, R132H and WT IDH1, respectively, and >100-fold selectivity over IDH2. (S,R)-WT IDH1 Inhibitor 2 induces decrease in intracellular 2-HG, abrogation of the myeloid differentiation block and induction of granulocytic differentiation at the level of leukemic blasts and more immature stem-like cells. (S,R)-WT IDH1 Inhibitor 2 can be used for research of acute myeloid leukemia (AML) and other cancers..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat