AA43279 cas: (354812-16-1)

nazwa: AA43279

nr katalogowy: GB40087-5

cas: 354812-16-1

producent: GLPBio

opakowanie: 5mg

cena: 1256,99 [Pln] (bez rabatu)

wyszukaj podobne produkty: 354812-16-1


szczegóły:

Formula: C12H12N2O2S. Molecular weight: 248,3. Synonym: AA43279 (354812-16-1) is a selective Nav1.1 activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 μM). In rat hippocampal brain slices it increased the firing activity of parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels..

właściwości

czystość: No data

czas dostawy: Do potwierdzenia przez Chemat