nazwa: BSJ–4–116
nr katalogowy: GC62263-25
cas: 2519823-34-6
producent: GLPBio
opakowanie: 25mg
cena: 2731,35 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2519823-34-6
Formula: C40H49ClN8O8S. Molecular weight: 837,38. Solubility: DMSO : 250 mg/mL (298.55 mM, Need ultrasonic). Storage: Store at -20°C. Synonym: BSJ-4-116 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. BSJ-4-116 downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation). BSJ-4-116 exhibits potent antiproliferative effects, alone and in combination with the poly(ADP-ribose) polymerase inhibitor Olaparib..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat