nazwa: Dienamide A2
nr katalogowy: GB40178-5
cas: 24738-51-0
producent: GLPBio
opakowanie: 5mg
cena: 1256,99 [Pln] (bez rabatu)
wyszukaj podobne produkty: 24738-51-0
Formula: C16H29NO. Molecular weight: 251,41. Synonym: Dienamide A2 (24738-51-0) is an analog of the natural amides occurring in Echinacea which represent a new class of cannabinomimetic compounds. This class of compounds modulates TNF α mRNA expression in human monocytes/macrophages via the CB2 receptor. Dienamide A2 binds to cannabinoid receptors with greater affinity than endogenous cannabinoids (Ki= ~60 and >1500 nM for CB2 and CB1 respectively). It elevates intracellular Ca levels in CB2-positive but not in CB2-negative cells and this effect was blocked by SR144528. It significantly inhibits LPS-induced TNF α and IL-1β expression in a CB2-independent manner..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat