nazwa: EHNA HCl
nr katalogowy: GB40191-10
cas: 51350-19-7
producent: GLPBio
opakowanie: 10mg
cena: 807,66 [Pln] (bez rabatu)
wyszukaj podobne produkty: 51350-19-7
Formula: C14H28N5O ? HCl. Molecular weight: 318,87. Solubility: H2O : 100 mg/mL (318.64 mM, Need ultrasonic), DMSO : 83.33 mg/mL (265.53 mM, ultrasonic and warming and heat to 60°C). Synonym: EHNA (51350-19-7) inhibits phosphodiesterase 2 (PDE2) (IC50 = 0.8 - 5.5 µM in a variety of tissues and species) over PDE1, PDE3, or PDE4 (IC50 values > 100 µM). It also inhibits adenosine deaminase (ADA), IC50 = 1.2 and 1.5 µM in human RBCs and astrocytoma cells, respectively, which may be responsible for its ability to induce apoptosis in malignant pleural mesothelioma cell lines. Because it blocks breakdown of adenosine to inosine and hypoxanthine, EHNA prevents formation of free radical substrates, protecting against cardiac reperfusion-mediated injury. It inhibits differentiation and maintains expression of pluripotency markers in hESCs, but not through inhibition of PDEs or ADA..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat