FD223 cas: (2050524-24-6)

nazwa: FD223

nr katalogowy: GC62973-5

cas: 2050524-24-6

producent: GLPBio

opakowanie: 5mg

cena: 1678,24 [Pln] (bez rabatu)

wyszukaj podobne produkty: 2050524-24-6


szczegóły:

Formula: C17H12ClN5O2S. Molecular weight: 385,83. Solubility: DMSO : 100 mg/mL (259.18 mM, Need ultrasonic). Storage: Store at -20°C. Synonym: FD223 is a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor. FD223 displays high potency (IC50=1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 exhibits efficient inhibition of the proliferation of acute myeloid leukemia (AML) cell lines by suppressing p-AKT Ser473 thus causing G1 phase arrest during the cell cycle. FD223 has potential for the research of leukemia such as AML..

właściwości

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czas dostawy: Do potwierdzenia przez Chemat