GPI–16552 cas: (443794-40-9)

nazwa: GPI–16552

nr katalogowy: GB40221-5

cas: 443794-40-9

producent: GLPBio

opakowanie: 5mg

cena: 1256,99 [Pln] (bez rabatu)

wyszukaj podobne produkty: 443794-40-9


szczegóły:

Formula: C33H30N2O3. Molecular weight: 502,62. Synonym: GPI-16552 (443794-40-9) is a novel potent inhibitor of poly(ADP-ribose) glycohydrolase (PARG), IC50=1.7 μM. Pre or post ischemia treatment (40 mg/kg) with GPI-16552 reduces brain infarct volumes in a rat model of cerebral ischemia. It modulates the inflammatory response to ischemia/reperfusion in a rat splanchnic artery occlusion model and reduces the degree of spinal cord inflammation and tissue injury after experimental spinal cord trauma. GPI-16552 synergizes with temozolomide in decreasing melanoma cell invasion and metastatic spreading in mice injected with B16 melanoma cells..

właściwości

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czas dostawy: Do potwierdzenia przez Chemat