nazwa: GSK J4 free base
nr katalogowy: GC12997-10
cas: 1373423-53-0
producent: GLPBio
opakowanie: 10mg
cena: 807,66 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1373423-53-0
Formula: C24H27N5O2. Molecular weight: 417,46. Solubility: <41.75mg/ml in DMSO, <41.75mg/ml in ethanol. Storage: Store at -20°C. Synonym: GSK J4 free base is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 μM, respectively. GSK J4 free base inhibits LPS-induced TNF- α production in human primary macrophages with an IC50 of 9 μM. GSK J4 is a cell permeable prodrug of GSK-J1. GSK J4 free base induces endoplasmic reticulum stress-related apoptosis..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat