nazwa: H–Gly–His–Arg–Pro–NH₂
nr katalogowy: GA22468-5
cas: 209623-54-1
producent: GLPBio
opakowanie: 5mg
cena: 1350,60 [Pln] (bez rabatu)
wyszukaj podobne produkty: 209623-54-1
Formula: C19H32N10O4. Molecular weight: 464,53. Solubility: Soluble in DMSO. Storage: Store at -20°C. Synonym: The central E region of fibrin contains two sets of polymerization knobs, A and B, that are cryptic in fibrinogen but become exposed after thrombin cleavage of fibrinopeptide A (FpA) and fibrinopeptide B (FpB) from the N-terminus of the A α- and Bβ-chains, respectively. The location of the binding holes and possible models for knob-hole interactions are known from X-ray crystallographic studies using synthetic peptide analogs of knobs A and B. When fibrinogen fragment D and double-D are crystallized in the presence of both peptide analogs, the knob A peptide mimic H-Gly-Pro-Arg-Pro-NH? (GPRP-amide, H-1998) forms H-bond interactions with residues γ364Asp, γ330Asp, γ329Gln, and γ340His found in hole a. In the same manner, the knob B peptide mimic H-Gly-His-Arg-Pro-NH? (GHRP-amide, H-7318) interacts with residues Bβ397Glu, Bβ398Asp, and Bβ432Asp in hole b..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat