nazwa: HM43239
nr katalogowy: GC63507-10
cas: 2294874-49-8,2569527-64-4
producent: GLPBio
opakowanie: 10mg
cena: 3784,46 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2294874-49-8,2569527-64-4
Formula: C29H33ClN6. Molecular weight: 501,07. Solubility: DMSO : 125 mg/mL (249.47 mM, Need ultrasonic). Storage: 4°C, protect from light. Synonym: HM43239 is an orally active and selective FLT3 inhibitor with IC50s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. HM43239 inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. HM43239 inhibits the proliferation and induces the apoptosis of leukemic cells..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat