nazwa: HOIPIN 11a – GSK11a
nr katalogowy: GB40233-5
cas: 1610800-91-3
producent: GLPBio
opakowanie: 5mg
cena: 3194,72 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1610800-91-3
Formula: C15H18N2O4. Molecular weight: 290,31. Synonym: Selective, cell-permeable and covalent inhibitor of the RBR E3 ubiquitin ligase HOIP. Biochemical characterization of HOIPIN 11a demonstrated that this compound labels HOIP with promising proteome-wide selectivity and effectively inhibits linear polyubiquitin chain formation in vitro and in a cellular environment. Treating HEK293T cells overexpressing full length HOIP, HOIL-1L, and SHARPIN with compound 11a overnight led to inhibition of NF- κB activation in a concentration-dependent manner, with an estimated IC50 value of 37 µM..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat