nazwa: I–138
nr katalogowy: GC69249-5.1
cas: 2098211-50-6
producent: GLPBio
opakowanie: 10mM (in 1ml dmso)
cena: 2221,17 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2098211-50-6
Formula: C26H23F3N6O. Molecular weight: 492,5. Storage: Store at -20°C. Synonym: I-138 is an orally effective compound structurally related to ML323. I-138 and ML323 are potent USP1-UAF1 reversible inhibitors. I-138 displays synergistic binding with ubiquitin and mutually exclusive binding with ML323. I-138 induces mono-ubiquitination of FANCD2 and PCNA in MDA-MB-436 cells, increasing mono-ubiquitination of PCNA and FANCD2 in HAP-1 USP1 WT cells. I-138 eliminates self-cleavage of USP1 in cells..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat