nazwa: INCB28060

nr katalogowy: GC17866-100

cas: 1029712-80-8

producent: GLPBio

opakowanie: 100mg

cena: 2253,94 [Pln] (bez rabatu)

wyszukaj podobne produkty: 1029712-80-8

szczegóły:

Formula: C23H17FN6O. Molecular weight: 412,42. Solubility: ≥ 5.15mg/mL in DMSO with gentle warming. Storage: Store at -20°C. Synonym: INCB28060 (INC280, INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor (IC50=0.13 nM). INCB28060 can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5. INCB28060 potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis. Antitumor activity. INCB28060 is largely metabolized by CYP3A4 and aldehyde oxidase..

właściwości

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czas dostawy: Do potwierdzenia przez Chemat