nazwa: M2912
nr katalogowy: GC25603-5
cas: 1460286-21-8
producent: GLPBio
opakowanie: 5mg
cena: 1004,24 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1460286-21-8
Formula: C17H18N2O2. Molecular weight: 282,34. Solubility: DMSO: 56 mg/mL (198.34 mM),Water: Insoluble,Ethanol: 6 mg/mL (21.25 mM). Storage: Store at -20°C. Synonym: M2912 (MSC2504877) is a very potent TNKS1/TNKS2 inhibitor (IC50=0.6 nM for TNKS1) with exquisite selectivity over other PARP family enzymes and favorable compound properties. This inhibitor potently modulates the Wnt/β-catenin pathway by elevating the levels of axin2 (EC50=17 nM) and tankyrase in DLD1 cells in a dose-dependent manner resulting in reduced cellular Wnt reporter activity..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat