nazwa: MD–224
nr katalogowy: GC38812-100
cas: 2136247-12-4
producent: GLPBio
opakowanie: 100mg
cena: 7786,29 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2136247-12-4
Formula: C48H43Cl2FN6O6. Molecular weight: 889,8. Solubility: DMSO: 150 mg/mL (168.58 mM), Water: < 0.1 mg/mL (insoluble). Storage: Store at -20°C. Synonym: MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept. MD-224 consists of ligands for Cereblon and MDM2. MD-224 induces rapid degradation of MDM2 at concentrations <1 nM in human leukemia cells, and achieves an IC50 value of 1.5 nM in inhibition of growth of RS4,11 cells. MD-224 has the potential to be a new class of anticancer agent..
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czas dostawy: Do potwierdzenia przez Chemat