nazwa: MS9427
nr katalogowy: GC69505-10
cas: 2772613-37-1
producent: GLPBio
opakowanie: 10mg
cena: 5048,20 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2772613-37-1
Formula: C48H58ClFN8O12. Molecular weight: 993,47. Solubility: DMSO : 70 mg/mL (70.46 mM, Need ultrasonic). Storage: 4°C, protect from light, stored under nitrogen. Synonym: MS9427 is an effective PROTAC EGFR degrader, with Kd values of 7.1 nM and 4.3 nM for wild-type EGFR and mutant EGFR L858R, respectively. MS9427 selectively degrades mutant variants through the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathway, but does not degrade WT EGFR. MS9427 has a strong inhibitory effect on NSCLC cell proliferation and can be used in cancer research..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat