nazwa: Metapristone – RU42633 | Desmethylmifepristone
nr katalogowy: GB40275-10
cas: 104004-96-8
producent: GLPBio
opakowanie: 10mg
cena: 2113,52 [Pln] (bez rabatu)
wyszukaj podobne produkty: 104004-96-8
Formula: C28H33NO2. Molecular weight: 415,57. Synonym: Metapristone, the primary metabolite of RU486 , suppressed NSCLC proliferation by promoting apoptosis via decrease the cellular EGFR-mediated PI3K/AKT pathways. In addition, metapristone inhibited anti-apoptotic marker Bcl-2, and activated pro-apoptotic key signaling proteins caspase-3, and poly (ADP-ribose) polymerase. Metapristone induced A549 and H1975 cell cycle via arrest at the G0-G1 stage. Moreover, metapristone inhibited endometrial cancer cell growth through suppressing cell proliferation and activating cell apoptosis-related signaling pathway. Mechanically, metapristone regulated miR-492 and its new target genes Klf5 and Nrf1 in vitro and in vivo to treat endometrial cancer..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat