nazwa: NB–360
nr katalogowy: GC65970-1
cas: 1262857-73-7
producent: GLPBio
opakowanie: 1mg
cena: 1088,49 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1262857-73-7
Formula: C21H19F4N5O2. Molecular weight: 449,4. Solubility: DMSO : 250 mg/mL (556.30 mM, Need ultrasonic). Storage: Store at -20°C. Synonym: NB-360 is a potent, brain penetrable, and orally bioavailable dual BACE1/BACE2 inhibitor (IC50: mouse and human BACE1=5 nM, BACE2=6 nM). NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in amyloid precursor protein(APP) transgenic mice. NB-360 can completely block the progression of Aβ deposition in the brains of APP transgenic mice. NB-360 shows excellent selectivity over the related aspartyl proteases pepsin, cathepsin D and cathepsin E..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat