NEO 212 – TMZ–POH cas: (1361198-79-9)

nazwa: NEO 212 – TMZ–POH

nr katalogowy: GB40295-5

cas: 1361198-79-9

producent: GLPBio

opakowanie: 5mg

cena: 2113,52 [Pln] (bez rabatu)

wyszukaj podobne produkty: 1361198-79-9


szczegóły:

Formula: C17H20N6O4. Molecular weight: 372,38. Synonym: Novel DNA alkylating agent exhibiting superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo (IC50 values 5-50 µM for cytotoxicity on glioma cell lines). NEO 212 causes DNA damage and cell death much more efficiently than TMZ, because linkage with POH increased its biological half-life and thus provided greater opportunity for placement of cytotoxic DNA lesions.NEO212 is a conjugate of temozolomide (TMZ) with the natural product perillyl alcohol (POH) and circumvents TMZ-resistance in multiple cancer cell lines and gliomas..

właściwości

czystość: No data

czas dostawy: Do potwierdzenia przez Chemat