nazwa: NX–2127
nr katalogowy: GC69600-10
cas: 2416131-46-7
producent: GLPBio
opakowanie: 10mg
cena: 2604,97 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2416131-46-7
Formula: C39H45N9O5. Molecular weight: 719,83. Solubility: DMSO : 100 mg/mL (138.92 mM, Need ultrasonic). Storage: 4°C, protect from light. Synonym: NX-2127 is an orally effective BTK inhibitor that can induce the degradation of mutated BTKC481S in cells. NX-2127 inhibits the proliferation of TMD8 cells with the BTKC481S mutation more effectively than Ibrutinib. NX-2127 catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3), corresponding to concentrations of 25 nM and 54 nM, respectively. NX-2127 stimulates T cell activation and increases IL-2 production in primary human T cells..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat