nazwa: PAWI–2
nr katalogowy: GB40312-5
cas: 1448427-02-8
producent: GLPBio
opakowanie: 5mg
cena: 2267,98 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1448427-02-8
Formula: C19H21N3O3S. Molecular weight: 371,45. Synonym: PAWI-2 is an inhibitor which targets both Wnt signaling (IC50 value of 11 nM) and ATM/p53 (EC50 value of 1.9 nM for p53). PAWI-2 binds tubulin and potently activates mitotic stress signaling to stabilize p53 and inhibit Wnt/β-catenin transactivation of downstream genes in colorectal cancer cells. Moreover, PAWI-2 inhibits cellular proliferation of androgen-sensitive and androgen-insensitive cells (LNCaP and PC-3, respectively)..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat