PCC0208017 cas: (2623158-64-3)

nazwa: PCC0208017

nr katalogowy: GC65253-10

cas: 2623158-64-3

producent: GLPBio

opakowanie: 10mg

cena: 2857,72 [Pln] (bez rabatu)

wyszukaj podobne produkty: 2623158-64-3


szczegóły:

Formula: C19H20F3N7. Molecular weight: 403,4. Solubility: DMSO : 125 mg/mL (309.87 mM, Need ultrasonic). Storage: Store at -20°C. Synonym: PCC0208017 is a microtubule affinity regulating kinases (MARK3/MARK4) inhibitor with IC50s of 1.8 and 2.01?nM, respectively. PCC0208017 has much lower inhibitory activity against MARK1 and MARK2, with IC50s of 31.4 and 33.7?nM, respectively. PCC0208017 suppresses glioma progression?in?vitro?and?in?vivo. PCC0208017 disrupts microtubule dynamics and induces G2/M phase cell cycle arrest and cell apoptosis. PCC0208017 demonstrates robust antitumor activity?in?vivo?and displays good BBB permeability..

właściwości

czystość: No data

czas dostawy: Do potwierdzenia przez Chemat