nazwa: S116836
nr katalogowy: GC63332-5
cas: 1257628-57-1
producent: GLPBio
opakowanie: 5mg
cena: 2520,73 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1257628-57-1
Formula: C27H21F3N6O. Molecular weight: 502,49. Solubility: DMSO : 65 mg/mL (129.36 mM, ultrasonic and warming and heat to 60°C). Storage: 4°C, stored under nitrogen. Synonym: S116836, a potent, orally active BCR-ABL tyrosine kinase inhibitor, blocks both wild-type as well as T315I Bcr-Abl. S116836 arrests the cells in the G0/G1 phase of cell cycle, induces apoptosis, increases ROS production, and decreases GSH production in BaF3/WT and BaF3/T315I cells. S116836 also inhibits SRC, LYN, HCK, LCK and BLK, and receptor tyrosine kinases such as FLT3, TIE2, KIT, PDGFR-β. Antitumor activies..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat