nazwa: SD–36
nr katalogowy: GC61270-1
cas: 2429877-44-9
producent: GLPBio
opakowanie: 1mg
cena: 4617,59 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2429877-44-9
Formula: C59H62F2N9O12P. Molecular weight: 1158,15. Solubility: DMSO: 150 mg/mL (129.52 mM). Storage: -20°C, stored under nitrogen. Synonym: SD-36 is a potent and efficacious STAT3 PROTAC degrader (Kd=~50 nM), and demonstrates high selectivity over other STAT members. SD-36 also effectively degrades mutated STAT3 proteins in cells and suppresses the transcriptional activity of STAT3 (IC50=10 nM). SD-36 exerts robust anti-tumor activity, and achieves complete and long-lasting tumor regression in mouse tumor models. SD-36 is composed of the STAT3 inhibitor SI-109, a linker, and an analog of Cereblon ligand Lenalidomide for E3 ubiquitin ligase..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat