nazwa: SEC inhibitor KL–1
nr katalogowy: GC38063-100
cas: 900308-84-1
producent: GLPBio
opakowanie: 100mg
cena: 4542,70 [Pln] (bez rabatu)
wyszukaj podobne produkty: 900308-84-1
Formula: C18H16ClNO4. Molecular weight: 345,78. Solubility: DMSO: 41.67 mg/mL (120.51 mM). Storage: Store at -20°C. Synonym: SEC inhibitor KL-1 (KL-1), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. SEC inhibitor KL-1 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with a Ki of 3.48 μM..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat