nazwa: WAY 262611 dihydrochloride
nr katalogowy: GB40410-10
cas: 2108968-58-5
producent: GLPBio
opakowanie: 10mg
cena: 2347,55 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2108968-58-5
Formula: C20H22N4.2HCl. Molecular weight: 391,34. Synonym: Inhibitor of Dickkopf-1 (DKK1), WAY 262611 is a wingless Wnt/β-Catenin signaling agonist with an inhibitory effect on DKK1, displaying an EC50 value of 0.63 μM for DKK1-mediated TCF-Luciferase, no affinity for GSK-3β (IC50 value >100 μM) and enhancing the bone formation rate in ovariectomized (OVX) rats following oral adminstration. Dickkopf-1 (DKK1) is a soluble inhibitor of Wnt-3a mediated Wnt/β-catenin signaling required for embryonic head development. It regulates Wnt signaling by binding to the Wnt coreceptor lipoprotein-related protein-5 (LRP5)/Arrow, and Kremen2 (Kr2) simultaneously..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat