nazwa: Xevinapant hydrochloride
nr katalogowy: GC63290-5
cas: 1071992-57-8
producent: GLPBio
opakowanie: 5mg
cena: 802,98 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1071992-57-8
Formula: C32H44ClN5O4. Molecular weight: 598,18. Solubility: DMSO : 175 mg/mL (292.55 mM, Need ultrasonic). Storage: Store at -20°C, sealed storage, away from moisture and light. Synonym: Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). Xevinapant hydrochloride binds to XIAP, cIAP1, and cIAP2 proteins with Kis of 66.4, 1.9, and 5.1 nM, respectively. Xevinapant hydrochloride effectively antagonizes XIAP BIR3 protein in a cell-free functional assay, induces rapid degradation of cellular cIAP1 protein, and inhibits cancer cell growth in various human cancer cell lines. Xevinapant hydrochloride is highly effective in induction of apoptosis in xenograft tumors..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat