nazwa: YKL–5–124 TFA
nr katalogowy: GC39462-5
cas: 2748220-93-9
producent: GLPBio
opakowanie: 5mg
cena: 1486,33 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2748220-93-9
Formula: C30H34F3N7O5. Molecular weight: 629,63. Solubility: DMSO: ≥ 100 mg/mL (158.82 mM). Storage: Store at -20°C. Synonym: YKL-5-124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively. YKL-5-124 TFA is >100-fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL-5-124 TFA induces a strong cell-cycle arrest, inhibits E2F-driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat