nazwa: YKL–5–124
nr katalogowy: GC62294-5
cas: 1957203-01-8
producent: GLPBio
opakowanie: 5mg
cena: 1491,02 [Pln] (bez rabatu)
wyszukaj podobne produkty: 1957203-01-8
Formula: C28H33N7O3. Molecular weight: 515,61. Solubility: DMSO : 250 mg/mL (484.86 mM, Need ultrasonic). Storage: Store at -20°C. Synonym: YKL-5-124 is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively. YKL-5-124 is >100-fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL-5-124 induces a strong cell-cycle arrest, inhibits E2F-driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat