nazwa: ZYF0033
nr katalogowy: GC69239-25
cas: 2380300-79-6
producent: GLPBio
opakowanie: 25mg
cena: 3328,58 [Pln] (bez rabatu)
wyszukaj podobne produkty: 2380300-79-6
Formula: C26H30N4O2S. Molecular weight: 462,61. Storage: Store at -20°C. Synonym: ZYF0033 (HPK1-IN-22, compound ZYF0033) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of less than 10 nM based on its inhibitory effect on MBP protein phosphorylation. ZYF0033 reduces the phosphorylation of SLP76 (serine 376). ZYF0033 promotes anti-cancer immune response. ZYF0033 inhibits tumor growth in the 4T-1 syngeneic mouse model and leads to increased infiltration of DC, NK cells, and CD107a+CD8+ T cells into tumors but decreased infiltration of T cells, PD-1+CD8+ T cells, TIM-3+CD8+ T cells, and LAG3+CD8+ T cells..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat