nazwa: iCRT5
nr katalogowy: GB40238-5
cas: 18623-44-4
producent: GLPBio
opakowanie: 5mg
cena: 1214,87 [Pln] (bez rabatu)
wyszukaj podobne produkty: 18623-44-4
Formula: C16H17NO5S2. Molecular weight: 367,44. Synonym: iCRT5 (18623-44-4) is a selective CRT (β-catenin-responsive transcription) inhibitor. IC50=18 nM for Wnt responsive STF16 luciferase. Acts via interfering with the β-catenin, TCF4 interaction. Displays poor inhibition of cell proliferation in triple-negative breast cancer cells. Increases the surface expression of MHCII, CD80 and CD86 on unstimulated dendritic cells (DCs) with no detrimental effects on immune-phenotype of stimulated DCs. Modulators of Wnt signaling show great promise in animal models of several cancers. Cell permeable..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat