nazwa: SAH–SOS1A TFA
nr katalogowy: GC62034-10
producent: GLPBio
opakowanie: 10mg
cena: 3363,22 [Pln] (bez rabatu)
wyszukaj podobne produkty: GC62034-10
Formula: C102H160N27F3O30. Molecular weight: 2301,55. Storage: Store at -20°C, protect from light, stored under nitrogen. Synonym: SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat