nazwa: SR 142948 dihydrochloride
nr katalogowy: GC69940-10
producent: GLPBio
opakowanie: 10mg
cena: 4079,33 [Pln] (bez rabatu)
wyszukaj podobne produkty: GC69940-10
Formula: C39H53Cl2N5O6. Molecular weight: 758,77. Solubility: H2O : 50 mg/mL (65.90 mM, Need ultrasonic), DMSO : 10 mg/mL (13.18 mM, Need ultrasonic). Storage: Store at -20°C. Synonym: SR 142948 dihydrochloride is an orally active and selective non-peptide antagonist of the neurotensin receptor (NT). Its IC50 values are 1.19 nM, 0.32 nM, and 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain respectively. SR 142948 dihydrochloride inhibits NT-induced inositol phosphate formation with an IC50 value of 3.9 nM in HT-29 cells. In vivo, it blocks NT-induced hypothermia, analgesia, and turning behavior. SR 142948 dihydrochloride can penetrate the blood-brain barrier and can be used for research on psychiatric disorders..
czystość: No data
czas dostawy: Do potwierdzenia przez Chemat