(S,E)-N-(4-((3,4-Difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide (Afatinib Impurity), 95%

cas: 2223677-62-9 — see every product listed under this CAS number, including other names

(S,E)-N-(4-((3,4-Difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide (Afatinib Impurity), 95% (CAS 2223677-62-9) is a chemical reagent available from Chemat. Available pack sizes: 50mg. Offered by: Chemat.

• 2D
• 3D

(E)-N-[4-(3,4-difluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide (CAS 2223677-62-9) is a chemical compound with the molecular formula C24H25F2N5O3 and a molecular weight of 469.5 g/mol. IUPAC name: (E)-N-[4-(3,4-difluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide. InChIKey: HGIMFDMPTIPMFG-CWDCEQMOSA-N.

Identity

Molecular formula	C24H25F2N5O3
Molecular weight	469.5 g/mol
IUPAC name	(E)-N-[4-(3,4-difluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
InChIKey	HGIMFDMPTIPMFG-CWDCEQMOSA-N
SMILES	CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)F)O[C@H]4CCOC4

Computed by PubChem (NCBI)

Synonyms: 3-Fluoro-Afatinib, Afatinib Impurity E, Afatinib Impurity E, Afatinib IMpurity SF, orb3181249

Isomers (same molecular formula)

(2R)-2-N-[1-(3,5-difluoro-4-hydroxyphenyl)pyrazol-3-yl]-1-N-(4-propan-2-ylphenyl)pyrrolidine-1,2-dicarboxamide C₂₄H₂₅F₂N₅O₃