4-((3-Chloro-4-fluorophenyl)amino)-6-(3-(morpholin-4-yl)propoxy)quinazolin-7-ol (O-Demethylgefitinib)

cas: 847949-49-9 — see every product listed under this CAS number, including other names

4-((3-Chloro-4-fluorophenyl)amino)-6-(3-(morpholin-4-yl)propoxy)quinazolin-7-ol (O-Demethylgefitinib) (CAS 847949-49-9) is a chemical reagent available from Chemat. Available pack sizes: 25mg. Offered by: Mikromol.

• 2D
• 3D

O-desmethyl Gefitinib is a member of quinazolines.

Source: ChEBI

Identity

Molecular formula	C21H22ClFN4O3
Molecular weight	432.9 g/mol
IUPAC name	4-(3-chloro-4-fluoroanilino)-6-(3-morpholin-4-ylpropoxy)quinazolin-7-ol
InChIKey	IFMMYZUUCFPEHR-UHFFFAOYSA-N
SMILES	C1COCCN1CCCOC2=C(C=C3C(=C2)C(=NC=N3)NC4=CC(=C(C=C4)F)Cl)O

Computed by PubChem (NCBI)

Synonyms: O-Desmethyl Gefitinib, 7-Quinazolinol,4-((3-chloro-4-fluorophenyl)amino)-6-(3-(4-morpholinyl)propoxy), 4-((3-Chloro-4-fluorophenyl)amino)-6-(3-morpholinopropoxy)quinazolin-7-ol, Gefitinib impurity E, 7-Quinazolinol,4-[(3-chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-, 4-[(3-Chloro-4-fluorophenyl)amino]-7-hydroxy-6-(3-morpholinopropoxy)quinazoline, Gefitinib impurity H, O-Demethyl-Gefitinib, O-DesmethylGefitinibmetabolite, Gefitinib O-Desmethyl Impurity

Isomers (same molecular formula)

7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid;hydrochloride C₂₁H₂₂ClFN₄O₃