8-Bromo-cGMP, 98%

cas: 31356-94-2 — see every product listed under this CAS number, including other names

8-Bromo-cGMP, 98% (CAS 31356-94-2) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.

brandChemat Brand
catalog numberACCFRH175
cas31356-94-2
sizeon request
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Available pack sizes

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properties

purity98%
delivery timeTo be confirmed by Chemat

8-bromo-3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. It has a role as a muscle relaxant and a protein kinase G agonist. It is a 3',5'-cyclic purine nucleotide and an organobromine compound. It is functionally related to a 3',5'-cyclic GMP.

Source: ChEBI

Identity
Molecular formulaC10H11BrN5O7P
Molecular weight424.10 g/mol
IUPAC name9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-8-bromo-1H-purin-6-one
InChIKeyYUFCOOWNNHGGOD-UMMCILCDSA-N
SMILESC1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=C(C(=O)NC(=N4)N)N=C3Br)O)OP(=O)(O1)O

Computed by PubChem (NCBI)