AZD8931 (Sapitinib)
cas: 848942-61-0 — see every product listed under this CAS number, including other names
AZD8931 (Sapitinib) (CAS 848942-61-0) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC13761-10 |
| cas | 848942-61-0 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 938.72 Pln | |
| GLPBio | 100mg | 3297.69 Pln | |
| GLPBio | 5mg | 676.61 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 704.69 Pln | |
| GLPBio | 50mg | 2347.55 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Sapitinib is a member of the class of quinazolines that is 4-amino-7-methoxyquinazoline in which the amino group has been substituted by a 3-chloro-2-fluorophenyl group and in which position 6 of the quinoline ring has been substituted by a {1-[2-(methylamino)-2-oxoethyl]piperidin-4-yl}oxy group. Sapitinib is a dual tyrosine kinase inhibitor (TKI) of epithelial growth factor receptors (EGFR) HER2 and HER3. It has a role as an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an epidermal growth factor receptor antagonist. It is a member of piperidines, an aromatic ether, a member of quinazolines, a secondary amino compound, a tertiary amino compound, a member of monochlorobenzenes and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C23H25ClFN5O3 |
|---|---|
| Molecular weight | 473.9 g/mol |
| IUPAC name | 2-[4-[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]-N-methylacetamide |
| InChIKey | DFJSJLGUIXFDJP-UHFFFAOYSA-N |
| SMILES | CNC(=O)CN1CCC(CC1)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC |
Computed by PubChem (NCBI)