Products 217082-58-1
CAS 217082-58-1 appears in our catalog under these names: Apelin–13, Apelin-13/ 96.81% (existing batch purity), Apelin-13, human, bovine , Apelin-13 (human, bovine, mouse, rat), APELIN-13. Offered by: GLPBio, TargetMol, Thermo Scientific (Alfa Aesar), Biosynth, Sigma-Aldrich. Available pack sizes: 1mg, 10mg, 25mg, 5mg, 50mg, 100mg, 5 mg, 1 mg.
Apelin-13 is a 13 amino acid oligopeptide which is the ligand for the apelin receptor (also known as the APJ receptor). It exhibits hypotensive and neuroprotective effects, and may be a potential prognostic biomarker for acute ischemic stroke and multiple sclerosis. It has a role as an antihypertensive agent, a biomarker, a neuroprotective agent, a human metabolite and an autophagy inhibitor. It is a conjugate base of an apelin-13(3+).
Source: ChEBI
| Molecular formula | C69H111N23O16S |
|---|---|
| Molecular weight | 1550.8 g/mol |
| IUPAC name | (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid |
| InChIKey | XXCCRHIAIBQDPX-PEWBXTNBSA-N |
| SMILES | CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCSC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N |
Computed by PubChem (NCBI)