Baricitinib (LY3009104, INCB028050)

cas: 1187594-09-7 — see every product listed under this CAS number, including other names

Baricitinib (LY3009104, INCB028050) (CAS 1187594-09-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 2mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC14844-10
cas1187594-09-7
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 938.72 Pln
GLPBio 100mg 2118.20 Pln
GLPBio 2mg 606.40 Pln
GLPBio 5mg 798.30 Pln
GLPBio 10mM (in 1ml dmso) 737.45 Pln
GLPBio 50mg 1495.70 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat

Baricitinib is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted by a 1-[3-(cyanomethyl)-1-(ethanesulfonyl)azetidin-3-yl]-1H-pyrazol-4-yl group at position 5. It is an FDA approved selective Janus Kinase 1 and 2 (JAK1 and JAK2) inhibitor used for the treatment of rheumatoid arthritis. It has a role as an antiviral agent, an immunosuppressive agent, an antirheumatic drug, an anti-inflammatory agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a nitrile, a member of pyrazoles, a sulfonamide, a pyrrolopyrimidine and a member of azetidines.

Source: ChEBI

Identity
Molecular formulaC16H17N7O2S
Molecular weight371.4 g/mol
IUPAC name2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
InChIKeyXUZMWHLSFXCVMG-UHFFFAOYSA-N
SMILESCCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3

Computed by PubChem (NCBI)

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