cas: 649735-63-7 — see every product listed under this CAS number, including other names
Brivanib (alaninate) 98% (CAS 649735-63-7) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A369272-1mg |
| cas | 649735-63-7 |
| size | 1mg |
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| brand | size | price | |
|---|---|---|---|
| Ambeed | 1mg | 242.44 Pln | |
| Ambeed | 2mg | 286.94 Pln | |
| Ambeed | 5mg | 337.00 Pln | |
| Ambeed | 10mg | 509.44 Pln | |
| Ambeed | 25mg | 932.19 Pln | |
| Ambeed | 50mg | 1544.06 Pln | |
| Ambeed | 100mg | 2567.56 Pln |
| purity | 98% |
|---|---|
| delivery time | 2-3 weeks |
| ambeed catalog no. | A369272 |
Brivanib alaninate is a carboxylic ester resulting from the formal condensation of the carboxy group of L-alanine with the hydroxy group of brivanib. It is a prodrug of brivanib (BMS-540215), a potent oral dual inhibitor of VEGFR-2 and FGFR-1 (IC50 of 25 nM and 148 nM, respectively) and was in development for the treatment of hepatocellular and colon carcinomas. It has a role as an antineoplastic agent, an angiogenesis inhibitor, a prodrug, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, a fibroblast growth factor receptor antagonist and an apoptosis inducer. It is a fluoroindole, a carboxylic ester, an aromatic ether, a diether, a L-alanine derivative and a pyrrolotriazine. It is functionally related to a brivanib.
Source: ChEBI
| Molecular formula | C22H24FN5O4 |
|---|---|
| Molecular weight | 441.5 g/mol |
| IUPAC name | [(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate |
| InChIKey | LTEJRLHKIYCEOX-OCCSQVGLSA-N |
| SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)OC(=O)[C@H](C)N)C |
Computed by PubChem (NCBI)