Brivanib (BMS–540215)
cas: 649735-46-6 — see every product listed under this CAS number, including other names
Brivanib (BMS–540215) (CAS 649735-46-6) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 2mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC11692-10 |
| cas | 649735-46-6 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1214.87 Pln | |
| GLPBio | 100mg | 5048.20 Pln | |
| GLPBio | 2mg | 709.37 Pln | |
| GLPBio | 5mg | 877.87 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 793.62 Pln | |
| GLPBio | 50mg | 3321.09 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Brivanib is a secondary alcohol resulting from the hydrolysis of the carboxylic ester group of brivanib alaninate. It is a dual VEGFR-2/FGFR-1 kinase inhibitor whose alanine prodrug, brivanib alaninate is currently under development as an oral agent for the treatment of cancer. It has a role as an antineoplastic agent, an angiogenesis inhibitor, a drug metabolite, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, a fibroblast growth factor receptor antagonist and an apoptosis inducer. It is a fluoroindole, an aromatic ether, a secondary alcohol, a diether and a pyrrolotriazine.
Source: ChEBI
| Molecular formula | C19H19FN4O3 |
|---|---|
| Molecular weight | 370.4 g/mol |
| IUPAC name | (2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-ol |
| InChIKey | WCWUXEGQKLTGDX-LLVKDONJSA-N |
| SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)O)C |
Computed by PubChem (NCBI)