Products 68-41-7
CAS 68-41-7 appears in our catalog under these names: D-Cycloserine, Cycloserine, D-Cycloserine, >95% (HPLC), D-Cycloserine/ 99.83% (existing batch purity), D–Cycloserine. Offered by: Chemat Brand, TRC, Mikromol, LoGiCal, Dr. Ehrenstorfer. Available pack sizes: on request, 100mg, 250mg, 5g, 10mg, 500mg, 50mg, 1g.
D-cycloserine is a 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and D-alanineD-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis). It has a role as a metabolite, an antitubercular agent, an antimetabolite, an antiinfective agent and a NMDA receptor agonist. It is a 4-amino-1,2-oxazolidin-3-one, an organonitrogen heterocyclic antibiotic and an organooxygen heterocyclic antibiotic. It is a conjugate base of a D-cycloserine(1+). It is an enantiomer of a L-cycloserine. It is a tautomer of a D-cycloserine zwitterion.
Source: ChEBI
| Molecular formula | C3H6N2O2 |
|---|---|
| Molecular weight | 102.09 g/mol |
| IUPAC name | (4R)-4-amino-1,2-oxazolidin-3-one |
| InChIKey | DYDCUQKUCUHJBH-UWTATZPHSA-N |
| SMILES | C1[C@H](C(=O)NO1)N |
Computed by PubChem (NCBI)
Synonyms:
D-cycloserine, cycloserine, Seromycin, orientomycin, Oxamycin, Cyclo-D-serine, Cicloserina, Farmiserina, Cyclorin, Tisomycin