Elexacaftor (Standard)

cas: 2216712-66-0 — see every product listed under this CAS number, including other names

Elexacaftor (Standard) (CAS 2216712-66-0) is a chemical reagent available from Chemat. Available pack sizes: Get quote. Offered by: MedChemExpress.

brand	MedChemExpress
catalog number	HY-111772R-Get quote
cas	2216712-66-0
size	Get quote
availability	Get quote

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Available pack sizes

brand	size	price
MedChemExpress	Get quote	price on request

properties

delivery time	to confirm by Chemat
purity	no data

Elexacaftor is a small molecule CFTR (cystic fibrosis transmembrane conductance regulator) corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation.

Source: ChEBI

Identity
Molecular formula	C₂₆H₃₄F₃N₇O₄S
Molecular weight	597.7 g/mol
IUPAC name	N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
InChIKey	MVRHVFSOIWFBTE-INIZCTEOSA-N
SMILES	C[C@H]1CC(N(C1)C2=C(C=CC(=N2)N3C=CC(=N3)OCC(C)(C)C(F)(F)F)C(=O)NS(=O)(=O)C4=CN(N=C4C)C)(C)C

Computed by PubChem (NCBI)

Synonyms: Elexacaftor, TRIKAFTA COMPONENT ELEXACAFTOR, Elexacaftor [USAN], N-Desmethyl Elexacaftor, ELEXACAFTOR [WHO-DD], Elexacaftor (USAN), ELEXACAFTOR COMPONENT OF TRIKAFTA, WJX, Elexacaftor?, ELEXACAFTOR [MI]