Entinostat (MS–275,SNDX–275)
cas: 209783-80-2 — see every product listed under this CAS number, including other names
Entinostat (MS–275,SNDX–275) (CAS 209783-80-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC11625-10 |
| cas | 209783-80-2 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 587.68 Pln | |
| GLPBio | 100mg | 924.67 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 597.04 Pln | |
| GLPBio | 50mg | 746.82 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Entinostat is a member of the class of benzamides resulting from the formal condensation of the carboxy group of the pyridin-3-ylmethyl carbamate derivative of p-(aminomethyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an inhibitor of histone deacetylase isoform 1 (HDAC1) and isoform 3 (HDAC3). It has a role as an antineoplastic agent, an EC 3.5.1.98 (histone deacetylase) inhibitor and an apoptosis inducer. It is a member of benzamides, a carbamate ester, a member of pyridines, a substituted aniline and a primary amino compound. It is functionally related to a 1,2-phenylenediamine.
Source: ChEBI
| Molecular formula | C21H20N4O3 |
|---|---|
| Molecular weight | 376.4 g/mol |
| IUPAC name | pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate |
| InChIKey | INVTYAOGFAGBOE-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3 |
Computed by PubChem (NCBI)
Synonyms:
Entinostat, ms-275, entinostatum, pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate, N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide, (pyridin-3-yl)methyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate, pyridin-3-ylmethyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate, N-(2-aminophenyl)-4-[N-(pyridin-3-ylmethoxycarbonyl)aminomethyl]benzamide, pyridin-3-ylmethyl N-((4-((2-aminophenyl)carbamoyl)phenyl)methyl)carbamate, (pyridin-3-yl)methyl N-((4-((2-aminophenyl)carbamoyl)phenyl)methyl)carbamate