Eptifibatide acetate

cas: 188627-80-7 — see every product listed under this CAS number, including other names

Eptifibatide acetate (CAS 188627-80-7) is a chemical reagent available from Chemat. Available pack sizes: 50mg. Offered by: Biosynth.

brandBiosynth
catalog numberFE40869-50mg
cas188627-80-7
size50mg
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Available pack sizes

brand size price
Biosynth 50mg price on request

properties

categoryLife Sciences
sub-category 1Ligands
sub-category 2Peptide Receptors
purityNo data
delivery time1-2 weeks

Eptifibatide is a synthetic homodetic cyclic peptide comprising Nalpha-(3-sulfanylpropanoyl)homoarginyl, glycyl, aspartyl, tryptophyl, prolyl and cysteinamide residues connected in sequence and cyclised via a disulfide bond. Derived from a protein found in the venom of the southeastern pygmy rattlesnake, Sistrurus miliarus barbouri, eptifibatide is an anti-coagulant that inhibits platelet aggregation by selectively blocking the platelet glycoprotein IIb/IIIa receptor, so preventing the binding of fibrinogen, von Willebrand factor, and other adhesive ligands. It is used in the management of unstable angina and in patients undergoing coronary angioplasty and stenting procedures. It has a role as an anticoagulant and a platelet aggregation inhibitor. It is a homodetic cyclic peptide, an organic disulfide and a macrocycle.

Source: ChEBI

Identity
Molecular formulaC35H49N11O9S2
Molecular weight832.0 g/mol
IUPAC name2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid
InChIKeyCZKPOZZJODAYPZ-LROMGURASA-N
SMILESC1C[C@H]2C(=O)N[C@@H](CSSCCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N

Computed by PubChem (NCBI)

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